Tirzepatide is a novel dual agonist peptide that targets both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, enhancing insulin secretion and reducing glucagon levels. This mechanism not only improves blood sugar control but also significantly aids in weight loss through appetite suppression, delayed gastric emptying, and enhanced lipid metabolism. 

Clinical trials have demonstrated that tirzepatide substantially reduces body weight. In one study, participants experienced a mean weight loss of 26.6% over 84 weeks, with those on tirzepatide achieving an additional 21.1% weight loss after 12 weeks of intensive lifestyle intervention. These results highlight tirzepatide's efficacy in promoting significant weight loss, especially when combined with healthy lifestyle changes. 

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